Patients aged 60 years and over wanting access to Moderna SPIKEVAX or Pfizer Comirnaty instead of AstraZeneca COVID19 vaccine:
A group of patients should avoid AstraZeneca a precautionary measure, and are recommended to receive Pfizer Comirnaty or Moderna SPIKEVAX instead:
These are patients with a past history of:
- cerebral venous sinus thrombosis (CVST)
- heparin induced thrombocytopenia (HIT)
- idiopathic splanchnic (mesenteric, portal, splenic) vein thrombosis, and
- antiphospholipid syndrome with thrombosis.
- patients with an allergic reaction to components of the AstraZeneca Vaccination or significant reaction to a first dose AstraZeneca vaccination.
Pfizer Comirnaty is recommended for the second dose for people in these groups who have received a first dose of COVID-19 Vaccine AstraZeneca.
Side effects of Pfizer Comirnaty COVID19 vaccination
You can view the full advice on what to expect after you vaccination at
Side effects are usually mild after the first dose of Pfizer , and usually go away within one or two days. You can take paracetamol or ibuprofen if you need to after your vaccinations. If there is swelling at the injection site, you can use a cold compress /ice pack.
Some recipients will experience more significant flu-like symptoms from this vaccination compared to other common vaccinations and may require time away from normal activities. This is more common after the second dose
Common side effects after Comirnaty include:
- pain or swelling at the injection site
- muscle pain
- fever and chills
- joint pain.
Less common side effects after Comirnaty include
- redness at the injection site
- enlarged lymph nodes
- feeling unwell
- pain in limb insomnia
- itching at the injection site.
Rare side effects that have been reported after Comirnaty are
- severe allergic reaction (anaphylaxis)
- myocarditis and pericarditis
Most reported cases have been mild, self-limiting and recovered quickly, although longer-term follow-up of these cases is ongoing. Cases have been reported predominantly after the second dose and predominantly in younger males (aged < 30 years)
As this is evolving please read the link for the latest information:
Who shouldn’t have Pfizer Comirnaty COVID19 vaccination?
The following groups should book a discussion appointment to seek additional advice from a Reydon Street Medical Centre GP before booking a vaccination appointment here.
- Myocarditis and pericarditis have been rarely reported after Comirnaty.
- People who develop myocarditis or pericarditis after having Comirnaty should defer further doses of Comirnaty and discuss this with their treating doctor.
- People with a past history of inflammatory heart condition illness e.g.:
- myocarditis, pericarditis,endocarditis within the last 3 months
- current acute rheumatic fever
- complex or severe congenital heart disease;
- acute decompensated heart failure (worsening of symptoms) or
- a history of cardiac transplant
These groups may still be able to receive Comirnaty or SPIKEVAX, however consultation with a your GP or cardiologist is recommended as a precaution prior to booking a vaccination appointment.
Past History of mastocytosis, allergy and anaphylaxis
Precautions to the use of COVID-19 Vaccines include a history of generalised (non-anaphylactic) reaction to a prior dose or an ingredient, past anaphylaxis to medications/vaccines which may contain polyethylene glycol or polysorbate 80, and a history of confirmed mastocytosis with recurrent anaphylaxis which requires treatment.
Precautions are required for people with a history of confirmed mastocytosis with recurrent anaphylaxis. Patients with other mast cell disorders can be vaccinated without special precautions.
This may affect choice of vaccine, location of delivery and requires a review appointment with your GP / specialist before booking a vaccination appointment
I have heard about possible allergies. What non-active ingredients are included in the Pfizer vaccine ?
None of the vaccine ingredients are of human or animal origin and there are no food, latex or gelatin in the COVID-19 vaccines that are currently available. If individuals have had an allergic reaction to other vaccines in the past, it does not mean that they will also be allergic to the COVID-19 vaccines (Australasian Society of Clinical Immunology and Allergy [ASCIA], 2021).
Patients with allergies to the ingredients in the vaccination will need to discuss COVID19 vaccination with their doctor.
The TGA list the following ingredients :
- ((4-hydroxybutyl)azanediyl)bis(hexane6,1-diyl)bis(2-hexyldecanoate) (ALC0315)
- 2-[(polyethylene glycol)-2000]-N,Nditetradecylacetamide (ALC-0159)
- Distearoylphosphatidylcholine (DSPC)
- Potassium chloride
- Monobasic potassium phosphate
- Sodium chloride
- Dibasic sodium phosphate dihydrate
- Water for injections